Positions

Selected Publications

Academic Article

Year Title Altmetric
2021-01-01 Mechanistic Investigation of Site-specific DNA Methylating Agents Targeting Breast Cancer Cells.Journal of Medicinal Chemistry..  64:12651–12669.. 2021-01-01
2019-01-01 Reactivity of N3-Methyl-2-Deoxyadenosine in Nucleosome Core Particles.Chem. Res. Toxicol..  32:2118-2124. 2019-01-01
2017-01-01 Glycoconjugated Site-selective DNA-Methylating Agent Targeting Glucose Transporters on Glioma Cells.Biochemistry.  56:421 – 440. 2017-01-01
2015-01-01 Oral TNFα modulation alters M1/M2 phenotype and neutrophil infiltration, improves cognition and diminishes Tau pathology in the 3xTgAD mouse modelPLoS ONE.  10:e0137305/1-e0137305/28. 2015-01-01
2009-01-01 Molecular Dynamics of d(CGCGAATTCGCG)2 Complexed with Netropsin and Its Minor Groove Methylating Analog, Me-lex, Using Explicit and Implicit Water ModelsJournal of Molecular Structure – Theochem.  894:50-58. 2009-01-01

Presentations

Principal Investigator On

  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2013-12-01 - 2014-11-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2012-12-01 - 2013-11-01
  • CSURF Undergraduate Research Supplies Award: DNA binding studies of site-specific minor groove binders 2013-02-01 - 2013-06-01
  • CSURF Undergraduate Research Supplies Award: DNA binding studies of site-specific minor groove binders 2013-02-01 - 2013-06-01
  • CSURF Undergraduate Research Supplies Award: DNA binding studies of site-specific minor groove binders 2013-02-01 - 2013-06-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2011-12-01 - 2012-12-01
  • DNA Binding Studies of Site-Specific Minor Groove Binders 2012-05-01 - 2012-08-01
  • CSURF Undergraduate Research Supplies Award: DNA binding studies of site-specific minor groove binders 2012-02-01 - 2012-06-01
  • CSURF Undergraduate Research Supplies Award: DNA binding studies of site-specific minor groove binders 2012-02-01 - 2012-06-01
  • Cahill Award: Cytotoxic, non-mutagenic DNA damage targeted to cells via glucose transporters 2011-01-01 - 2011-12-01
  • CSURF Undergraduate Research Supplies Award: DNA binding studies of site-specific minor groove binders 2011-02-01 - 2011-06-01
  • Synthesis of a Cancer Cell Selective DNA-Methylating Agent 2010-05-01 - 2010-08-01
  • Selective protein-capture using surface modified nanoporous alumina membranes 2008-12-01 - 2009-12-01
  • Cytotoxic, Non-mutagenic DNA-methylating Agents Targeting Estrogen Receptor Positive Cells 2008-07-01 - 2009-12-01
  • Enhancing Undergraduate Research and Creativity Award
  • Investigator On

  • Acquisition of an NMR console and probe to support research and education 2021-08-01 - 2024-07-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2021-11-01 - 2022-11-01
  • A1 Biochemical Laboratories Postdoctoral Fellowship 2016-07-01 - 2022-04-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2020-11-01 - 2021-11-01
  • Synthesis of Key Intermediates for Anti-Breast Cancer DNA Damaging Agent 2021-01-01
  • Synthesis of Key Intermediates for Anti-Prostate Cancer DNA Damaging Agent 2021-01-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2019-11-01 - 2020-11-01
  • Novel DNA-damaging chemotherapeutics targeting breast cancer cells. 2019-10-01 - 2020-05-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2018-11-01 - 2019-11-01
  • A Targeted Chemotherapeutic for Treating ER+ Breast Cancer 2019-01-01
  • Design and Synthesis of Molecules for Causing Lethal DNA Double Strand Breaks 2019-01-01
  • Development of Site-Specific DNA Damaging Agents Targeting Cancer Cells 2019-01-01
  • Novel DNA-Damaging Chemotherapeutics Targeting Breast Cancer Cells 2019-01-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2017-10-01 - 2018-11-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2016-06-01 - 2018-11-01
  • Analytical Characterization of Novel Chemotherapy Drugs 2018-01-01
  • Design and Synthesis of Molecules for Causing Lethal DNA Double Strand Breaks 2018-01-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2015-06-01 - 2017-11-01
  • Small Molecules Targeting G-Quadruplexes for Anti-Cancer Therapy 2017-01-01
  • Small Molecules Targeting G-Quadruplexes for Anti-Cancer Therapy, research conducted at the Indian Institute of Technology Bombay, India 2017-01-01
  • Small Molecules Targeting G-Quadruplexes for Anti-Cancer Therapy, research conducted at the Indian Institute of Technology Bombay, India 2017-01-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2014-05-01 - 2015-11-01
  • Analysis of DNA damage caused by anti-cancer compounds 2015-01-01
  • Improving uptake of site-specific DNA damaging agents in breast cancer cells using Ladder Frame Polyethers 2014-01-01 - 2015-01-01
  • Small molecule TNF alpha inhibitors as oral Treatments for Alzheimer’s Disease 2014-01-01 - 2015-01-01
  • Synthesis of novel compounds for treatment of neuro-inflammatory diseases 2013-12-01 - 2014-11-01
  • UNCW Summer Undergraduate Research and Creativity Award 2014-01-01
  • Acquisition of a 600MHz NMR 2009-08-01 - 2012-08-01
  • Full Name

  • Sridhar Varadarajan