Selected Publications
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Academic Article
- The Cancer Prevention Project of Philadelphia: preliminary findings examining diversity among the African diaspora.. Ethn Health.. 26:659-675.. 2021-07-01
- Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail.. Elife. 1:e65369.. 2021-02-01
- Methodological Innovations Drive Conceptual Innovations Forward in Chromatin Biology. Methods. 1:1-3. 2020-10-01
- Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems.. Cells. 8. 2019-09-01
- Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation.. Nucleic Acids Research. 47:7380-7391. 2019-08-01
- One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry.. Genome Res. 29:978-987. 2019-05-01
- IL-35 (Interleukin-35) Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial Reactive Oxygen Species-Mediated Site-Specific Acetylation of H3K14 (Histone 3 Lysine 14).. Arterioscler Thromb Vasc Biol.. 38:599-609.. 2018-01-01
- S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice.. Mol Genet Metab Rep.. 15:15-21. 2018-01-01
- Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.. Clin Cancer Res.. 24:1375-1388. 2018-01-01
- T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.. J Cell Sci.. 131. 2018-01-01
- An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis.. Cancer Res.. 77:5026-5038.. 2017-01-01
- HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides.. J Biol Chem.. 292:21568-21577. 2017-01-01
- Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe.. Elife.. 18. 2017-01-01
- Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non-Small Cell Lung Cancer Cells.. Mol Cancer Ther.. 16:1596-1609. 2017-01-01
- Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels.. J Biol Chem.. 292:3312-3322. 2017-01-01
- Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.. J Pharmacol Exp Ther.. 361:140-150. 2017-01-01
- ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.. Cell Rep.. 17:1037-1052.. 2016-01-01
- Global Profiling of Acetyltransferase Feedback Regulation.. J Am Chem Soc.. 2016-01-01
- Interaction with the DNA Repair Protein Thymine DNA Glycosylase Regulates Histone Acetylation by p300.. Biochemistry.. 55:6766-6775.. 2016-01-01
- Lack of global epigenetic methylation defects in CBS deficient mice.. J Inherit Metab Dis.. 40:113-120. 2016-01-01
- Modulation of p300/CBP acetylation of nucleosomes by bromodomain ligand I-CBP112.. Biochemistry. 55:3727-34.. 2016-01-01
- Measuring specificity in multi-substrate/product systems as a tool to investigate selectivity in vivo.. Biochim. Biophys. Acta. 1864:70-6. 2015-08-01
- Site specificity analysis of Piccolo NuA4-mediated acetylation for different histone complexes.. Biochem. J.. 2015-01-01
- Targeting calcium signaling induces epigenetic reactivation of tumor suppressor genes in cancer.. Cancer Res.. 2015-01-01
- Utilizing targeted mass spectrometry to demonstrate Asf1-dependent increases in residue specificity for Rtt109-Vps75 mediated histone acetylation.. PLoS One. 10. 2015-01-01
- A quantitative multiplexed mass spectrometry assay for studying the kinetic of residue-specific histone acetylation.. Methods.. 70:127-33. 2014-08-01
- Changing the selectivity of p300 by acetyl-CoA modulation of histone acetylation.. ACS Chem. Biol.. 2014-01-01
- Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth.. Mol. Cancer. 13. 2014-01-01