Scholars
@UNCW
Scholars
@UNCW
Edit My Profile
Browse
Browse
Home
People
Organizations
Research
Events
Capability Map
Frampton, Arthur Ronald
Associate Professor
Close
E-mail
framptona@uncw.edu
Phone
910.962.2643
Visualizations
Co-author Network
Co-investigator Network
Frampton, Arthur Ronald
Associate Professor
Positions
Associate Professor
,
Biology and Marine Biology
,
College of Science and Engineering
Publications
Research
Teaching
Contact
Publications
Selected Publications
Academic Article
Filter
Year
Title
Altmetric
2021-01-01
Mechanistic investigation of site-specific DNA methylating agents targeting breast cancer cells.
.
Journal of Medicinal Chemistry.
. 64:12651–12669..
2021-01-01
2017-01-01
Glycoconjugated Site-selective DNA-Methylating Agent Targeting Glucose Transporters on Glioma Cells.
.
Biochemistry
. 56:421-440..
2017-01-01
2016-01-01
Equine herpesvirus type 1 modulates inflammatory host immune response genes in equine endothelial cells.
.
Veterinary Microbiology
. 192:52-59..
2016-01-01
2015-12-01
Impact of Anxiety and Depressive Symptoms on Perceptions of Stigma in Persons Living with HIV Disease in Rural versus Urban North Carolina.
.
AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV.
. 27:1425-1428.
2015-12-01
2015-01-01
Impact of anxiety and depressive symptoms on perceptions of stigma in persons living with HIV disease in rural versus urban North Carolina
.
AIDS Care
. 27:1425-1428.
2015-01-01
2014-01-01
Equine herpesvirus type 4 (EHV-4) uses a restricted set of equine major histocompatibility complex class I proteins as entry receptors.
.
Journal of General Virology.
. 95:1554-1563..
2014-01-01
2012-03-01
Equine herpesvirus type 1 mediated oncolysis of glioblastoma multiforme cells
.
Journal of Virology
. 86:2882-2886.
2012-03-01
2010-07-01
Equus Caballus Major Histocompatibility Complex Class I is an Entry Receptor for equine herpesvirus type 1
.
Journal of Virology
. 84:9027-9034.
2010-07-01
Presentations
COVID-19 pandemic.
,
Interviewed on WHQR Coastline program
2020-03-18
Determining viral presence in local tunicate populations.
,
UNCW Spring Student Research and Creativity Showcase.
2019-04-01
Targeting human cancer cells using novel compounds designed to bind to Sigma-1 receptors that are overexpressed in tumors.
,
UNCW Spring Student Research and Creativity Showcase.
2019-04-01
Testing novel compound EMS2CH2 on tamoxifen resistant estrogen receptor positive (ER+) breast cancer cells and their targeted kill rates.
,
UNCW Spring Student Research and Creativity Showcase.
2019-04-01
Identification of the Major Capsid Protein Gene for Megalocytivirus in Various Ascidian Tunics.
,
UNCW Spring Student Research and Creativity Showcase.
2018-04-17
Will the flu shot protect you and other virology questions....
,
Interviewed on WHQR’s Coastline radio show.
2018-02-08
Virus Hunting in Ascidians (Sea Squirts).
,
UNCW Fall Student Research and Creativity Showcase.
2017-11-20
Virus Hunting in Ascidians (Sea Squirts).
,
State of North Carolina Undergraduate Research and Creativity Showcase (SNURCS).
2017-11-04
Overexpression of the CD40 receptor enhances equine herpesvirus type 1 (EHV-1) mediated oncolysis of human U251 glioma cells.
,
36th Annual Meeting of the American Society for Virology
2017-06-23
Assessing the oncolytic potential of equine herpesvirus 1 (EHV-1) for U2OS, a human osteosarcoma.
,
2017 UNCW Spring Student Research and Creativity Showcase.
2017-03-28
CD40 as a potential entry receptor for EHV-1.
,
2017 UNCW Spring Student Research and Creativity Showcase.
2017-03-28
Recombinant EHV-1 vaccine development with deletion in DNA Polymerase.
,
2017 UNCW Spring Student Research and Creativity Showcase.
2017-03-28
The effect of non-steroidal anti-inflammatory drugs on pro-inflammatory cytokine expression following equine herpesvirus-1 infection.
,
2017 UNCW Spring Student Research and Creativity Showcase.
2017-03-28
CD40 increases oncolysis of GBM cells.
,
North Carolina American Society for Microbiology 2016 Meeting
2016-10-01
An analysis of EHV-1 glycoprotein mediated cell-to-cell fusion.
,
UNCW Fall Student Research & Creativity Showcase.
2015-10-27
Unraveling the mechanisms of EHV-1 pathogenesis informs the development of a novel oncolytic vector.
,
Invited speaker at Appalachian State University at the Department of Biology
2015-10-07
Generation of a DNA polymerase knockout in equine herpesvirus-1.
,
North Carolina American Society for Microbiology 2015 Meeting
2015-10-03
Valproic acid modulates the host immune response in glioma cells and sensitizes these cells to equine herpesvirus type 1 (EHV-1) infection.
,
34th Annual Meeting of the American Society for Virology
2015-07-01
Infection of equine endothelial cells with non-neurovirulent equine herpesvirus-1 strain KyA elicits greater down regulation of inflammatory cytokines CCL3, IL8, TGF-2β and CXCL3 compared to neurologic strain OHIO 2003.
,
North Carolina American Society for Microbiology 2014 Meeting
2014-09-27
Downregulation of the toll-like receptor 4 pathway contributes to enhanced killing of human glioma cells by equine herpesvirus type 1.
,
Thirteenth Southeastern Regional Virology Conference
2014-04-01
novel antivirals from marine microorganisms.
,
Wilmington Star News
2014-01-01
Assessing the suitability of Amp-N as a potential antiviral compound against EHV-1 infection
,
7th Annual Undergraduate Research and Creativity Showcase
2012-04-18
Evaluation of newly synthesized DNA methylating compounds for cellular specificity with chemotherapeutic applications
,
7th Annual Research and Creativity Showcase
2012-04-18
Equine herpesvirus type 1 (EHV-1) mediated oncolysis of glioblastoma multiforme cells
,
Twelfth Southeastern Regional Virology Conference
2012-03-11
,
10th Annual NC OPT-ED Alliance Day
2011-10-14
Equine herpesvirus type 1 (EHV-1) mediated oncolysis of human glioblastoma multiforme cells
,
2011 North Carolina American Society for Microbiology
2011-10-08
Equus Caballus MHC-I is an entry receptor for EHV-1
,
The Third Havemeyer EHV-1 Workshop
2011-09-18
Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1)
,
Graduate Student Symposium
2011-04-28
Investigation of the antiviral activity of a novel marine compound on equine herpesvirus 1 (EHV-1)
,
6th Annual Undergraduate Research and Creativity Showcase
2011-04-19
Investigation of the antiviral activity of a novel marine compound on equine herpesvirus 1 (EHV-1)
,
Undergraduate research Symposium
2011-04-10
Assessing the use of equine herpesvirus type 1 (EHV-1) as a possible oncolytic agent for human glioblastoma multiforme (GBM)
,
6th Annual Undergraduate Research and Creativity Showcase
2011-04-01
Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1)
,
Mid-Atlantic Microbial Pathogenesis Meeting
2011-01-31
Exploration of equine herpesvirus-1 (EHV-1) as an oncolytic agent for human glioblastoma multiforme (GBM)
,
Mid-Atlantic Microbial Pathogenesis Meeting
2011-01-30
Equus caballus is an entry receptor for equine herpesvirus type 1 (EHV-1)
2011-01-18
Design of compounds for N3-adenine methylation in cells expressing the GLUT2 glucose transporter
,
Southeast Regional Meeting of the American Chemical Society at New Orleans
2010-12-01
Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1)
2010-11-16
Equus Caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1)
,
North Carolina American Society for Microbiology 2010 Meeting
2010-10-02
Exploration of equine herpesvirus-1 (EHV-1) as an oncolytic agent for human glioblastoma multiforme (GBM)
,
North Carolina American Society for Microbiology 2010 Meeting
2010-10-02
Use of short interfering RNAs (siRNAs) to investigate which equine herpesvirus type 1 (EHV-1) glycoproteins are essential for infection
,
University of North Carolina Board of Governors' Meeting
2010-09-10
Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1)
,
35th International Herpesvirus Workshop
2010-07-24
Antiviral effects of marine compounds against equine herpesvirus type 1
,
UNCW Health-Related Studies Annual Research Symposium
2010-04-09
Early activation of the cell signaling protein, focal adhesion kinase (FAK) upon equine herpesvirus type 1 (EHV-1) infection
,
UNCW Health-Related Studies Annual Research Symposium
2010-04-09
Use of short interfering RNAs (siRNAs) to investigate which equine herpesvirus type 1 (EHV-1) glycoproteins are essential for infection
,
UNCW Health-Related Studies Annual Research Symposium
2010-04-09
Use of short interfering RNAs to investigate the role of specific tegument proteins in the intracellular movement of EHV-1 capsids at early times post-infection
,
UNCW Health-Related Studies Annual Research Symposium
2010-04-09
Equus caballus MHC class I is an entry receptor for equine herpesvirus type 1 (EHV-1)
,
11th Southeastern Regional Virology Conference
2010-03-19
Antiviral effects of marine compounds against equine herpesvirus type 1
,
5th Annual State of North Carolina Undergraduate Research & Creativity Symposium
2009-11-21
Early activation of the cell signaling protein, focal adhesion kinase (FAK) upon equine herpesvirus type 1 (EHV-1) infection.
,
5th Annual State of North Carolina Undergraduate Research & Creativity Symposium
2009-11-21
Use of short interfering RNAs (siRNAs) to investigate the role of specific tegument proteins in the intracellular movement of EHV-1 capsids at early times post-infection.
,
5th Annual State of North Carolina Undergraduate Research & Creativity Symposium
2009-11-21
Use of short interfering RNAs (siRNAs) to investigate which equine herpesvirus type 1 (EHV-1) glycoproteins are essential for infection.
,
5th Annual State of North Carolina Undergraduate Research & Creativity Symposium
2009-11-21
Equine herpesvirus type 1 (EHV-1) utilizes microtubules, dynein, ROCK1, and FAK to productively infect cells
,
34th International Herpesvirus Workshop
2009-07-25
The transport of equine herpesvirus type 1 (EHV-1) capsids to the nucleus requires microtubules, dynein, and the cellular kinase, ROCK1
,
Conference on Health and Related Sciences
2008-01-01
Research
Research Overview
Herpesviruses
Principal Investigator On
Cell signaling/receptor molecules for EHV-1 infection
2009-04-01 - 2012-03-01
Investigation of equine herpesvirus 1 (EHV-1), as a novel therapeutic for the treatment of human glioblastoma brain tumors.
2009-05-01 - 2010-04-01
Examination of cell signaling proteins activated by equine herpesvirus type 1 (EHV-1)
2009-03-01 - 2010-03-01
Co-principal Investigator On
Acquisition of a FEI Tecnai G2 Spirit BioTWIN Transmission Electron Microscope
2012-08-01 - 2013-12-01
Chemical and biological studies of an antiviral compound from a marine dinoflagellate
2011-06-01 - 2013-09-01
UNCW Introductory Biotechnology Workshop for High School Teachers
- 2011-01-01
Roche applied science (RAS) GS junior system for high throughput DNA sequence core facility at the Center for Marine Science, University of North Carolina Wilmington
Investigator On
Inhibiting EHV-1 with anti-inflammatory drugs.
2020-04-01 - 2022-03-01
NC Wastewater pathogen tracking research network.
2020-05-01 - 2020-12-01
UNC Research Collaboratory: NC Wastewater pathogen tracking research network.
2020-05-01 - 2020-12-01
Inhibition of equine herpesvirus 1 infection using non-steroidal anti-inflammatory drugs.
2019-10-01 - 2020-05-01
Novel DNA-damaging chemotherapeutics targeting breast cancer cells.
2019-10-01 - 2020-05-01
The First Ascidian Virome: A Novel Pathogen Reservoir in Coastal Habitats.
2018-01-01
Equipment Allocation: CFX96 Touch Real-Time PCR Detection System
2016-04-01
Identification of equine herpsevirus type 1 (EHV-1) neurovirulence determinants.
2012-12-01 - 2015-12-01
Molecular determinants of EHV-1 fusion and spread.
2013-04-01 - 2015-03-01
Identification of EHV-1 virulence factors.
2012-12-01 - 2014-12-01
Characterization of the specific viral and cellular factors required for the entry and replication of neurologic equine herpesvirus type 1 (EHV-1)
2012-12-01 - 2013-12-01
Virotherapy as a means of treating human brain cancer
2013-05-01 - 2013-06-01
ENHANCING APPLIED LEARNING THROUGH EXPLORATIONS OF THE NATURAL WORLD
2011-08-01 - 2012-05-01
Isolation and characterization of novel anti-EHV-1 compounds
2009-08-01 - 2010-07-01
ELx800 microplate reader and Gen5 software workstation to support the discovery and development of novel drugs derived from marine microorganisms.
2012-06-01 -
Teaching
Teaching Overview
Cell Biology Microbiology Virology
Contact
Full Name
Arthur
Ronald
Frampton