Halkides, Christopher J

Halkides, Christopher J
Professor

Professor, Chemistry and Biochemistry , College of Science and Engineering

Selected Publications

Academic Article

Year	Title	Altmetric
2019-01-01	Inactivation of Vaccinia H1 related phosphatase in the presence of phosphonomethylating agents. Journal of Undergraduate Chemistry Research . 18:6-10. 2019-01-01
2018-01-01	Synthesis of Proposed Inhibitors of the Enzyme Aspartate-β-Semialdehyde Dehydrogenase. Journal of Undergraduate Chemistry Research. 17:12-16. 2018-01-01
2018-01-01	Synthesis of a Stable Analog of the Phosphorylated Form of CheY: Phosphono-CheY. Bacterial Chemosensing Methods and Protocols Methods in Molecular Biology. 2018-01-01
2015-01-01	Assembly states of FliM and FliG within the flagellar switch complex. Journal of Molecular Biology. 427:867-86. 2015-01-01
2013-05-01	Using Molecular Models To Show Steric Clash in Peptides: An Illustration of Two Disallowed Regions in the Ramachandran Diagram. Journal of Chemical Education. dx.doi.org/10.1021/ed3001528:3 pages. 2013-05-01
2012-10-01	A carotenoid anti-oxidant extracted from bacterial populations in swine waste lagoons. Agricultural Science. 2012-10-01
2008-09-01	The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides. Archives of Biochemistry and Biophysics/Elsevier. 479:105-113. 2008-09-01
2007-10-01	A thermodynamic and crystallographic study of complexes of the highly preorganized ligand 8-hydroxyquinoline-2-carboxylic acid. Inorganica Chimica Acta. 361:1937-1946. 2007-10-01
2007-01-01	Introducing Michaelis-Menten Kinetics Through Simulation. Journal of Chemical Education. 84:434-437. 2007-01-01

Chapter

Year	Title	Altmetric
2017-01-01	Presumptive and Confirmatory Blood Testing. Forensic Science Reform Protecting the Innocent. 2017-01-01

Presentations

Production of a stable analog of the cysteinyl phosphate intermediate of VHR phosphatase, Reception following Larry Overman Seminar 2019-04-01
Production of a stable analog of the cysteinyl phosphate intermediate of VHR phosphatase, Southeast Regional Meeting of the American Chemical Society 2017-11-01
Forensic Failures in the Stallings, Chamberlain, Knox/Sollecito and Lundy Cases, UNCW Chemistry Club 2016-02-01
Synthesis characterization and crystallization of phosphono-CheY from Thermotoga maritima, Steenbock Symposium 2014-05-22
Teaching the steady-state and Michaelis-Menten kinetics to undergraduates, Steenbock Symposium 2014-05-22
Synthesis characterization and crystallization of phosphono-CheY from Thermotoga maritima, Signal Transduction in Microorganism - Gordon Research Conference 2014-01-12
Syntheses of Proposed Inhibitors of Aspartate-β-Semialdehyde Dehydrogenase, SERMACS 2012 2012-11-15
Forensic Failures in the Stallings and Knox/Sollecito cases, Eastern North Carolina Sectional 2012-04-11
Syntheses of potential bisubstrate analogs of aspartate semialdehyde dehydrogenase, SERMACS 2011-10-27
Forensic failures in the Stallings and the Knox/Sollecito cases, Haines Lecture I 2011 2011-04-20
Production of a stable analog of CheY-phosphate, a signal transduction protein in bacterial chemotaxis, Haines Lecture II 2011 2011-04-20
NMR Characterization of a Carotenoid from Hog Lagoons,” , North Carolina NMR Symposium 2010-04-12
“NMR Characterization of a Carotenoid from Hog Lagoons,” , UNCW Health-Related Studies Annual Research Symposium 2010-04-09

Research Overview

structure and function of phosphorylated forms of bacterial response regulators, structure of dual specificity phosphatases in phosphorylated form, inhibitors of aspartate semialdehyde deydrogenase, purification of spirilloxanthin and related carotenoids.

Principal Investigator On

Synthesis of phosphono-CheY and phosphono-VHR 2010-05-01 - 2014-04-01

Co-principal Investigator On

High sensitivity calorimetry instrumentation to study interactions in biochemical systems 2009-04-01 - 2010-03-01

Investigator On

Academic Enhancement Award: Synthesis of phosphono-CheY and phosphono-VHR 2010-04-01 - 2015-03-01

Acquisition of a 600MHz NMR 2009-08-01 - 2012-08-01

CSURF Supply Award 2021-01-01 -

CSURF Sprint Supply Award 2020-01-01 -

College of Arts & Sciences Pilot Grant Award 2019-01-01 -

Vinylsulfone Inhibitors of ASADH 2019-01-01 -

Synthesis of novel inhibitors of aspartate semialdehyde dehydrogenase 2018-01-01 -

CSURF Research Supply award 2017-01-01 -

Synthesis of novel bisubstrate analogs for aspartate semialdehyde dehydrogenase 2015-01-01 -

CSURF Research Supply Award 2000-01-01 -

Teaching Overview

Biochemistry lecture I and II, biochemistry lab, organic chemistry I, organic chemistry lab I and II

Full Name

Christopher J Halkides

Halkides, Christopher J Professor

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