Baden, Daniel G

Baden, Daniel G
Professor

Professor, Chemistry and Biochemistry , College of Science and Engineering
Director, Chemistry and Biochemistry , College of Science and Engineering 1999-07-15 -

Selected Publications

Academic Article

Year	Title	Altmetric
2016-04-01	Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish. PLoS ONE. 11:19. 2016-04-01
2014-09-01	Development of a fluorescence assay for the characterization of brevenal binding to rat brain synaptosomes. Journal of Natural Products. 77:2014-2020. 2014-09-01
2012-09-01	Development of a competitive fluorescence-based synaptosome binding assay for brevetoxins. Harmful algae. 19:85-91. 2012-09-01
2010-01-01	Absolute configuration of brevisamide and brevisin: confirmation of a universal biosynthetic process for Karenia brevis polyethers. Journal of Natural Products. 73:1177-1179. 2010-01-01
2010-01-01	Characterization of Novel Polyether Compounds Isolated from the Marine Dinoflagellate Karenia brevis. Journal of Natural Products/ACS. 73:536-540. 2010-01-01
2010-01-01	UV and Solar TIO2 photocatalysis of brevetoxins (PbTx’s). Toxicon. 55:195-203. 2010-01-01
2009-02-01	Brevisin: an aberrant polycyclic ether structure from the dinoflagellate Karenia brevis and its implications for polyether assembly.. Journal of Organic Chemicals. 74:94. 2009-02-01
2009-01-01	Ciguatoxin-induced catecholamine secretion in bovine chromaffin cells: mechanism of action. Toxicon. 2009-01-01
2009-01-01	Total synthesis and structural confirmation of brevisamide, a new marine cyclic ether alkaloid from the dinoflagellate Karenia brevis. Organic Letters. 11:217-220. 2009-01-01
2008-10-01	Brevenal Inhibits Pacific Ciguatoxin-1B-Induced Neurosecretion from bovine chromaffin cells. PLos one. 3:1-9. 2008-10-01
2008-08-01	Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons.. JPET. 326:13. 2008-08-01
2008-01-01	Brevisimide: an unprecedented monocyclic ether alkaloid from the dinoflagellate Karenia brevis that provides a potential model for ladder-frame initiation.. Organic Letters. 10:3465-3468. 2008-01-01
2008-01-01	Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons. JPET. 326:604-613. 2008-01-01
2007-01-01	An electrochemiluminescence-based competitive displacement immunoassay for the type-2 brevetoxins in oyster extracts. J AOAC Int.. 90:8. 2007-01-01

Presentations

Biopharmaceutical Industry Workforce Training: Coursework with Applied Learning Leads to Success, National Institute for Innovation in Manufacturing Biopharmaceuticals National Meeting 2019-06-01
Partnership for Workforce Development in the Biopharmaceutical Industry, National Institute for Innovation in Manufacturing Biopharmaceuticals National Meeting 2019-06-01
Determining Functional Effects of Brevetoxin and Brevetoxin Antagonists, 7th Symposium on Harmful Algae in the U.S. 2013-06-01
The MARBIONC Program at UNCW 2012-11-15
Isolation and localization of a non ribosomal peptide synthetase / polyketide synthase complex from the toxic dinoflagellate Karenia brevis., Microbial Genomics & Metagenomics Workshop 2008-01-01

Research Overview

toxin receptors, natural ligands as therapeutics, toxicology, marine natural products

Principal Investigator On

Partnership for Workforce Development in the BioPharmaceutical Industry 2018-06-01 - 2019-11-01

Effects of Inhaled Florida Red Tide 2006-07-01 - 2011-06-01

Effects of Inhaled Florida Red Tide Brevetoxins 2006-07-01 - 2011-06-01

MARBIONC, Marine biotechnology in North Carolina 2004-07-01 -

Co-principal Investigator On

Cooperative Institute for Ocean Exploration, Research, and Technology (CIOERT) 2009-07-01 - 2014-06-01

Development of High Affinity Analogues of Brevenal: Novel Molecular Probes for Neuronal Sodium Channels 2011-09-01 - 2013-08-01

CIOERT Task 3.3.2.1. New Technology Development to Measure In Situ Metabolism and Bioenergetics in Corals: 2009-11-01 - 2012-07-01

Cooperative Institute for Ocean Exploration, Research and Technology 2010-07-01 - 2011-06-01

Diverse Chemical Libraries from Photosynthetic Marine Microalgae 2005-12-01 - 2009-12-01

Center of Innovation in Marine Biotechnology 2008-01-01 -

Investigator On

Intraspecific variation in a toxin-producing dinoflagellate 2006-07-01 - 2009-06-01

Effects of Inhaled Florida Red Tide Brevetoxins 2000-08-01 - 2005-07-01

Teaching Overview

disruptive technology, permanent innovation, harmful algae, molecular pharmacology

Full Name

Daniel G Baden

Assignee

Fused Pentacyclic Polyethers Patent

Fused Pentacyclic Polyethers Patent

Ladder- Frame Polyether Conjugates Patent

Polyether Brevetoxin Derivatives as a Treatment for Cystic Fibrosis, Mucociliary Dysfunction, and Pulomonary Diseases Patent

Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases Patent

Polyether brevetoxin derivatives as a treatment for neurotoxic shellfish poisoning and ciguatera fish poisoning Patent

fused pentacyclic polyethers Patent

polyether breventoxin derivatives as treatment for cystic fibrosis, mucociliry dysfunction and pulmonary disesese Patent