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Andrews, Andrew J
Professor
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E-mail
andrewsaj@uncw.edu
Phone
910.962.2554
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Andrews, Andrew J
Professor
Positions
Professor
,
Chemistry and Biochemistry
,
College of Science and Engineering
Publications
Research
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Additional Document Info
Publications
Selected Publications
Academic Article
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Year
Title
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2021-07-01
The Cancer Prevention Project of Philadelphia: preliminary findings examining diversity among the African diaspora.
.
Ethn Health.
. 26:659-675..
2021-07-01
2021-02-01
Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail.
.
Elife
. 1:e65369..
2021-02-01
2020-10-01
Methodological Innovations Drive Conceptual Innovations Forward in Chromatin Biology
.
Methods
. 1:1-3.
2020-10-01
2019-09-01
Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems.
.
Cells
. 8.
2019-09-01
2019-08-01
Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation.
.
Nucleic Acids Research
. 47:7380-7391.
2019-08-01
2019-05-01
One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry.
.
Genome Res
. 29:978-987.
2019-05-01
2018-01-01
IL-35 (Interleukin-35) Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial Reactive Oxygen Species-Mediated Site-Specific Acetylation of H3K14 (Histone 3 Lysine 14).
.
Arterioscler Thromb Vasc Biol.
. 38:599-609..
2018-01-01
2018-01-01
S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice.
.
Mol Genet Metab Rep.
. 15:15-21.
2018-01-01
2018-01-01
Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.
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Clin Cancer Res.
. 24:1375-1388.
2018-01-01
2018-01-01
T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.
.
J Cell Sci.
. 131.
2018-01-01
2017-01-01
An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis.
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Cancer Res.
. 77:5026-5038..
2017-01-01
2017-01-01
HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides.
.
J Biol Chem.
. 292:21568-21577.
2017-01-01
2017-01-01
Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe.
.
Elife.
. 18.
2017-01-01
2017-01-01
Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non-Small Cell Lung Cancer Cells.
.
Mol Cancer Ther.
. 16:1596-1609.
2017-01-01
2017-01-01
Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels.
.
J Biol Chem.
. 292:3312-3322.
2017-01-01
2017-01-01
Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.
.
J Pharmacol Exp Ther.
. 361:140-150.
2017-01-01
2016-01-01
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.
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Cell Rep.
. 17:1037-1052..
2016-01-01
2016-01-01
Global Profiling of Acetyltransferase Feedback Regulation.
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J Am Chem Soc.
.
2016-01-01
2016-01-01
Interaction with the DNA Repair Protein Thymine DNA Glycosylase Regulates Histone Acetylation by p300.
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Biochemistry.
. 55:6766-6775..
2016-01-01
2016-01-01
Lack of global epigenetic methylation defects in CBS deficient mice.
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J Inherit Metab Dis.
. 40:113-120.
2016-01-01
2016-01-01
Modulation of p300/CBP acetylation of nucleosomes by bromodomain ligand I-CBP112.
.
Biochemistry
. 55:3727-34..
2016-01-01
2015-08-01
Measuring specificity in multi-substrate/product systems as a tool to investigate selectivity in vivo.
.
Biochim. Biophys. Acta
. 1864:70-6.
2015-08-01
2015-01-01
Site specificity analysis of Piccolo NuA4-mediated acetylation for different histone complexes.
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Biochem. J.
.
2015-01-01
2015-01-01
Targeting calcium signaling induces epigenetic reactivation of tumor suppressor genes in cancer.
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Cancer Res.
.
2015-01-01
2015-01-01
Utilizing targeted mass spectrometry to demonstrate Asf1-dependent increases in residue specificity for Rtt109-Vps75 mediated histone acetylation.
.
PLoS One
. 10.
2015-01-01
2014-08-01
A quantitative multiplexed mass spectrometry assay for studying the kinetic of residue-specific histone acetylation.
.
Methods.
. 70:127-33.
2014-08-01
2014-01-01
Changing the selectivity of p300 by acetyl-CoA modulation of histone acetylation.
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ACS Chem. Biol.
.
2014-01-01
2014-01-01
Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth.
.
Mol. Cancer
. 13.
2014-01-01
Research
Co-principal Investigator On
Metabolic and Epigenetic Reprogramming in Cyclin E High Ovarian Cancer
2021-05-01 - 2023-04-01
Investigator On
The Role of Histone Chaperones in Histone Acetylation and Nucleosome Dynamics
2014-09-01 - 2024-07-01
Defining an Acetyl-CoA-Sensing Mechanism as a Form of Intraorganelle Communication in Cancer
2018-06-01 - 2023-05-01
Trained Immunity in Chronic Kidney Disease-Accelerated Vascular Inflammation
2022-01-01
Contact
Full Name
Andrew
J
Andrews
Additional Document Info
Assignee
Combinations to Treat Cancer.
Patent